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The classic Golgi studies by Cajal (Ramón y Cajal S 1909-1911 Histologie du système nerveux de l'homme et des vertébrés. Maloine, Paris) and Lorente de Nó R (1934 Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system. J Psychol Neurol (Lpz) 46:113-177) showed the presence of some 20 different types of interneurons in the Hippocampus. Most of them have been immunohistochemically defined (see Freund TF, Buzsaki G 1996 Interneurons of the hippocampus. Hippocampus 6:347-470; Somogyi P 2010 Hippocampus: Intrinsic organization. In: Shepherd GM, Grillner S, eds: Handbook of Brain Microcircuitry. Oxford University Press, New York, pp 148-164). Some 28 types of GABAergic interneurons can be distinguished (Somogyi 2010), basically: Basket neurons, Bistratified neurons, and Chandelier neurons.
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